# Leakage-Proof Evaluation NeuroTwin v1 treats split construction as part of the scientific claim. Rules: - Build `SplitManifest` from recording-level metadata before preprocessing, augmentation, or windowing. - Use held-out subject, site, and dataset splits as primary tests. - Run record-ID reuse checks for every split. - For subject-held-out claims, no subject can appear across train/val/test. - For site-held-out claims, no site can appear across train/val/test. - For dataset-held-out claims, no dataset can appear across train/val/test. - Clinical prediction is secondary and cannot rescue a weak Neural Translation result. Main failure modes to catch: - Subject identity leakage. - Scanner/site leakage. - Repeated-session leakage. - Stimulus or clip leakage. - Metadata labels that encode the target. - Training windows generated before split assignment.